Prof. Dr. med. Katja Zirlik
Specialist in Haematology FMHSpecialist in Medical Oncology FMH
Core competencies
Treatment of tumor and blood disorders; FMH General Internal Medicine and Hematology; Hematology and Oncology (D)
Highly specialized in the treatment of hematological diseases
Career path
Since 2022
Founding partner and medical staff member at Tumor & BrustZentrum Ostschweiz
2016-present
Oncology consultation / consultation service at Schiers Hospital
2016-2022
Medical activity as a practicing internist specializing in hematology and internal oncology at the ZeTuP Tumor Center Chur
2011-2016
Senior Physician in the Department of Hematology, Oncology and Stem Cell Transplantation at the Medical University Hospital of Freiburg (Prof. Dr. Dr. h.c. R. Mertelsmann, since 2012 Prof. Dr. J. Duyster)
11/2012
Specialist in Hematology and Oncology
12/2010
Habilitation (postdoctoral qualification) in Internal Medicine entitled “Impacting survival-relevant anti-apoptotic signaling pathways as a therapeutic approach for chronic lymphocytic leukemia,” Faculty of Medicine, University of Freiburg
11/2008
Board certification in Internal Medicine
2005-2011
Research Associate / Ward Physician, Department of Hematology and Oncology and Stem Cell Transplantation, University Hospital Freiburg i.Br. (Prof. Dr. Dr. h.c. R. Mertelsmann)
2003-2005
Postdoctoral Fellow, (Prof. Dr. John G. Gribben, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA), Research Fellowship from the German
Cancer Aid, Research focus: Immunotherapy of chronic lymphocytic leukemia
Teaching activities
2001-2016
Teaching position at the Faculty of Medicine, Albert Ludwig University, Freiburg im Breisgau: Main lecture "Internal Medicine," lecture "Molecular Biology in Internal Medicine," seminar Internal Medicine "Solid Tumors," course "Clinical Chemistry and Hematology," seminar Internal Medicine "Hematology," course "Internal Medicine"
Since 2016 Course
"Internal Medicine," bedside teaching for students in higher semesters
Memberships
- American Society of Hematology
- German Society for Hematology and Oncology
- Working Group for Internal Oncology
- Swiss Group for Clinical Cancer Research (SAKK)
- Swiss Society for Medical Oncology
Courses & Certificates
- November 2007 Course for investigator including GCP training
- November 2012 Course for Coordinating Investigators
- September 2015 GCP Refresher
- March 2019 GCP Certificate (GCP-E6(R2) 2016)
- March 2020 Course for Genetic Counseling in Oncology, SAKK
Publications
Zirlik K, Veelken H.
Recent Results Cancer Res. 2018;212:243-264.
Dietrich S, Oleś M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, Oleś AK, Słabicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T.
Drug-perturbation-based stratification of blood cancer. J Clin Invest. 2018 Jan 2;128(1):427-445.
Zirlik K, Duyster J.
Anti-Angiogenics: Current Situation and Future Perspectives. Oncol Res Treat. 2018;41(4):166-171.
Gentile M, Shanafelt TD, Mauro FR, Reda G, Rossi D, Laurenti L, Del Principe MI, Cutrona G, Angeletti I, Coscia M, Herishanu Y, Chiarenza A, Molica S, Ciolli S, Goldschmidt N, Angrilli F, Giordano A, Rago A, Bairey O, Tripepi G, Chaffee KG, Sameer PA, Vigna E, Zirlik K, Shvidel L, Innocenti I, Recchia AG, Di Raimondo F, Del Poeta G, Cortelezzi A, Neri A, Ferrarini M, Gaidano G, Kay NE, Polliack A, Foà R, Morabito F.
Eur J Haematol. 2018 Jul 24.
Gentile M, Shanafelt TD, Reda G, Mauro FR, Zirlik K, Ciolli S, Laurenti L, Del Principe MI, Rossi D, Di Renzo N, Molica S, Angrilli F, Coscia M, Chiarenza A, Giordano A, Cutrona G, Chaffee KG, Parikh SA, Uccello G, Innocenti I, Tripepi G, D’Arrigo G, Vigna E, Recchia AG, Herishanu Y, Shvidel L, Tadmor T, Cortelezzi A, Del Poeta G, Gaidano G, Di Raimondo F, Neri A, Ferrarini M, Foà R, Polliack A, Morabito F.
Validation of a biological score to predict response in chronic lymphocytic leukemia patients treated front-line with bendamustine and rituximab. Leukemia. 2018 Aug;32(8):1869-1873.
Simon-Gabriel CP, Foerster K, Saleem S, Bleckmann D, Benkisser-Petersen M, Thornton N, Umezawa K, Decker S, Burger M, Veelken H, Claus R, Dierks C, Duyster J, Zirlik K.
Microenvironmental stromal cells abrogate NF-κB inhibitor-induced apoptosis in chronic lymphocytic leukemia. Haematologica. 2018 Jan;103(1):136-147.
Zirlik K, Duyster J
Combination of Antiangiogenics and Other Targeted Therapies
Springer International Publishing AG 2017
- Marmé (ed.), Tumor Angiogenesis
Benkisser-Petersen M, Buchner M, Dörffel A, Dühren-von-Minden M, Claus R, Kläsener K, Leberecht K, Burger M, Dierks C, Jumaa H, Malavasi F, Reth M, Veelken H, Duyster J, Zirlik K. Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia.
PLoS One. 2016 Dec 30;11(12).
